Date of Completion
IAPP is an amyloid protein that misfolds, causing toxic aggregation in the pancreas of Type II Diabetes patients. In this study, three metal cations (KCl, CaCl2, and CuCl2) are tested in Thioflavin T assays and atomic force microscopy (AFM) to see if they inhibit the aggregation of IAPP.
Burke, Megan, "Investigating Metal Cations as Potential Inhibitors of IAPP Aggregation: KCl, CaCl2, and CuCl2" (2016). Honors Thesis. 106.