Thicker than blood: Conserved mechanisms in Drosophila and vertebrate hematopoiesis

Authors

Cory J. Evans, University of California, Los AngelesFollow
Volker Hartenstein, University of California, Los Angeles
Utpal Banerjee, University of California, Los Angeles

Document Type

Article

Publication Date

2003

Abstract

Blood development in Drosophila melanogaster shares several interesting features with hematopoiesis in vertebrates, including spatiotemporal regulation as well as the use of similar transcriptional regulators and signaling pathways. In this review, we describe what is known about hematopoietic development in Drosophila and the various cell types generated and their functions. Additionally, the molecular genetic mechanisms of hematopoietic cell fate determination and commitment within Drosophila blood cell lineages are discussed and compared to vertebrate mechanisms.

Original Publication Citation

Evans, Cory & Hartenstein, Volker & Banerjee, Utpal. (2003). Thicker Than Blood: Conserved Mechanisms in Drosophila and Vertebrate Hematopoiesis. Developmental Cell. 5. 673-90.

Digital Commons @ LMU & LLS Citation

Evans, Cory J.; Hartenstein, Volker; and Banerjee, Utpal, "Thicker than blood: Conserved mechanisms in Drosophila and vertebrate hematopoiesis" (2003). Biology Faculty Works. 56.
https://digitalcommons.lmu.edu/bio_fac/56