Start Date
15-12-2015 11:35 AM
Description
Cells are able to perform different functions in response to conditions in their environment through regulated gene expression. This gene expression is regulated byproteins called transcription factors which can turn genes “on” or “off” depending on fwhat the cell needs, and these proteins can either work together in networks or workon their own. These networks and interactions between proteins can be expressedusing math and computer science to form a network “graph.” My project will be toexpress the mathematical properties of the network in a way which can help usersbetter understand the relationships of these proteins. To do this, I will research graph theory and implement it in an already-created gene regulatory network for the transcription factors which control a response to cold shock in budding yeast, Saccharomyces cerevisiae.
The Marriage of Biology and Applied Mathematics
Cells are able to perform different functions in response to conditions in their environment through regulated gene expression. This gene expression is regulated byproteins called transcription factors which can turn genes “on” or “off” depending on fwhat the cell needs, and these proteins can either work together in networks or workon their own. These networks and interactions between proteins can be expressedusing math and computer science to form a network “graph.” My project will be toexpress the mathematical properties of the network in a way which can help usersbetter understand the relationships of these proteins. To do this, I will research graph theory and implement it in an already-created gene regulatory network for the transcription factors which control a response to cold shock in budding yeast, Saccharomyces cerevisiae.
